| Effects of lower-limb exoskeleton robotic-assisted gait training on walking ability in stroke patients with hemiplegia |
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| DOI：10.3870/zgkf.2026.08.001 |
| EN KeyWords: lower-limb exoskeleton robot stroke motor function walking ability |
| Fund Project:安徽省临床医学研究转化专项(202427b10020018)；安徽省教育厅高校自然重点项目（2023AH053157）；安徽医科大学第二附属医院国家自然科学基金孵育计划（2023GMFY04）；安徽省转化医学研究院科研基金项目（2022zhyx-C75） |
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| EN Abstract: |
| Objective: To investigate the efficacy of lower-limb exoskeleton robotic-assisted gait training (RAGT) on improving the walking ability of stroke patients, thereby providing objective evidence for the optimization of clinical gait rehabilitation protocols.Methods: Totally, 36 eligible stroke patients were randomly allocated to the RAGT group and the control group, with 18 participants in each group. Both groups received routine rehabilitation therapy; additionally, the RAGT group underwent RAGT, while the control group received conventional gait training. The intervention duration was 2 weeks. Pre- and post-intervention assessments were conducted to evaluate the lower limb Brunnstrom stage, Functional Ambulation Category (FAC) score, Modified Barthel Index (MBI) score, and gait parameters (including walking speed, stride length, step width, toe out angle, and the proportion of single-step time contributed by the affected limb) in patients from both groups. Results: No statistically significant differences were found in all baseline characteristics between the two groups (P<0.05). After the intervention, both groups demonstrated significant improvements in lower limb Brunnstrom stage, FAC, MBI, walking speed, stride length, and the proportion of single-step time contributed by the affected limb compared with pre-intervention levels (P<0.05), while toe out angle was significantly reduced (P<0.05). Post-intervention intergroup comparisons revealed that the robot group had higher scores in lower limb Brunnstrom stage, walking speed, stride length, and the proportion of single-step time contributed by the affected limb than the control group (P<0.05), and the magnitude of reduction in toe out angle was greater in the robot group (P<0.05). Additionally,the robot group exhibited a significant reduction in step width after the intervention compared with baseline (P<0.05), but no significant intergroup difference was noted in this parameter. Conclusion: RAGT can effectively improve lower limb motor function and gait parameters in stroke patients, demonstrating potential clinical application value. |
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