| The impact of hyperbaric oxygen therapy on blood pressure: mechanism, evidence and rehabilitation significance |
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| DOI：10.3870/zgkf.2026.08.010 |
| EN KeyWords: hyperbaric oxygen therapy blood pressure vasoconstriction rehabilitation treatment cardiovascular effect |
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| View Counts: 459 |
| PDF Download Counts: 210 |
| EN Abstract: |
| Hyperbaric oxygen therapy increases the partial pressure of oxygen in tissues by inhaling high-concentration oxygen and is widely used in the rehabilitation treatment of ischemic and hypoxic diseases. During hyperbaric oxygen therapy, the hyperoxic environment can induce systemic vasoconstriction, bradycardia and decreased cardiac output, thereby causing blood pressure fluctuations. This article systematically expounds the physiological mechanisms by which hyperbaric oxygen therapy affects blood pressure, including the regulation of vascular endothelial function mediated by nitric oxide, changes in the balance of sympathetic and vagus nerves, and the activation of the baroreflex. It summarizes the characteristics and magnitudes of blood pressure changes in clinical studies, analyzes the differences in responses between hypertensive patients and non-hypertensive individuals, explores the modifying effects of different antihypertensive drugs on the impact of hyperbaric oxygen therapy on blood pressure, and sorts out the blood pressure response characteristics of special populations such as chronic kidney disease patients. On this basis, it also elaborates on the clinical significance of the blood pressure effects of hyperbaric oxygen therapy and its application value in rehabilitation medicine, providing a basis for the optimization of clinical treatment plans and the formulation of blood pressure management strategies. |
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